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Clinical observation of continuous veno-venous hemofiltration on patients with septic shock |
Wang Xiao-bo, Yang Ning, Huang Wan, Zhang Li, Pei Hong-hong |
Department of Emergency Intensive Care Unit, the Second Affiliated Hospital of Xi′an Jiaotong University, Xi′an 710004, China |
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Abstract Objective To investigatethe application of continuous veno-venous hemofiltration(CVVH) therapy in the treatment of patients with sepsis shock. Methods Seventy two cases of sepsis shock patients were selected form emergency intensive care unit(EICU) in our hospital.All the patients were divided into observation group(n=33) and control group(n=39). Control group were given the conventional treatment, however, the observation group were given the CVVH therapy. Symptom,pulse, the dosage of norepinephrine, lactic and ICU stay time were compared between the two groups. Results Compared the two groups, the age, pulse, the dosage of norepinephrine, lactic was of no statistical significant difference (P>0.05). After 12 hours CVVH therapy, the observation group had a decreased level of pulse, the dosage of norepinephrine, lactic and ICU stay time had a statistical significant difference (P<0.05). Conclusion The CVVH therapy can effectively improve the sepsis shock patients clinical indicators, improve the inadequate tissue perfusion, shorten the patients ICU stay time.
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Corresponding Authors:
Pei Hong-hong, E-mail: 18991237562@163.com
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[1]Seymour CW, Lin VX, Iwashyna TJ, et al. Assessment of clinical criteria for sepsis:for the third international consensus definitons for sepsis and septic shock[J]. JAMA, 2016, 315(8): 762-774.
[2]Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000[J]. N Engl J Med, 2003, 348(16):1546-1554.
[3]Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock, 2012[J]. Crit Care Med, 2013, 41(2):580-637.
[4]苏伟,黄昭,王思蓉,等.血液灌流联合连续性血液滤过治疗脓毒症并急性肾损伤[J].中国血液净化, 2011, 10(10):596-602.
[5]Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock(sepsis-3)[J]. JAMA, 2016, 315(8):801-810.
[6]师灵灵, 韩艳秋, 任慧娟,等.脓毒症的病理生理机制研究进展[J].中华医院感染学杂志, 2016, 26 (8):1914-1916.
[7]马丽娜.脓毒症炎症反应相关因子与预后[J].中国急救医学, 2011, 31(5):461-463.
[8]薛春利,李挺,徐俊赐,等.连续性血液净化疗法在烧伤脓毒血症治疗中的临床效果分析[J].临床医学工程, 2014, 21(2):147-148.
[9]Boussekey N, Chiche A, Faure K, et al. A pilot randomized study comparing high and low volume hemfliltration on vasopressor use in septic shock[J]. Intensive Care Med, 2008, 34(9):1646-1653.
[10]李跃东,王锦权,邵敏.连续性血液净化对重症脓毒症患者血乳酸水平及6h乳酸清除率的影响[J].安徽医科大学学报, 2014, 49(2):251-253,257.
[11]Joannidis M. Continuous renal replacement therapy in sepsis and multisystem organ failure[J]. Semin Dial, 2009, 22(2):160-164. |
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