|
|
|
|
|
| Assessment of the value of APACHEⅡ score system，SOFA score and procalcitonin in Acinetobacter baumannii bloodstream infection |
| Zhou Wen-Jie, Zhang Xiao-Ya, Zhang Jun, Wang Xiao-Hong, Yang Xiao-Jun, Ma Xi-Gang |
|
|
|
Abstract Objective To explore acute physiology and chronic health evaluation Ⅱ（APACHE Ⅱ）, sequential organ failure assessment（SOFA）score and procalcitonin in Acinetobacter baumannii bloodstream infection. Methods Clinical data was collected on 112 patients with Acinetobacter baumannii bloodstream infections during January 2009 to December 2015, including gender, age, APACHE Ⅱscore at admission and APACHEⅡ score on bloodstream infections day, SOFA score at admission and SOFA score on blood stream infections day, procalcitonin, length of ICU stay, the total hospitalization days, body temperature, white blood cell count, neutrophilic granulocyte percentage, 28 d end etc. The receiver operating characteristic curve（ROC）was drawn and the area under the curve（AUC）was calculated. APACHE Ⅱ, SOFA score and procalciton in Acinetobacter baumannii bloodstream infections in patients were compared to assess the value of prognosis. Results In 112 patients, 66 cases died（58.93%）, 46 cases survived（41.07%）. Compared with group survival, death group admission APACHEⅡ score（20.47±7.39 vs.12.59±5.26, P＜0.001）, bloodstream infections on APACHEⅡ score（26.56±8.16 vs.13.09 ± 4.99, P＜0.001）, admission SOFA score（8.94 ± 4.17 vs. 5.11 ± 2.44, P＜0.001）, bloodstream infections on SOFA score（11.86 ± 4.72 vs. 4.24 ± 3.06, P＜0.001）were significantly increased.Death and survival group, two groups of procalcitonin comparative difference was statistically significant（P＜0.001）. Individual indicators in the bloodstream infections on APACHE Ⅱ score prediction value
was the largest, AUC value of 0.920（95% CI 0.871~0.969）, when the cutoff value of 16, the sensitivity of 92.4%, 78.3% specific degrees. PCT joint bloodstream infections on APACHE Ⅱ score and SOFA score the AUC value was 0.935（95% CI 0.893~0.977）, in the joint index prediction value was bigger. Conclusion APACHEⅡ score, SOFA score and procalcitonin can be used as Acinetobacter baumannii bloodstream infection prognostic index. PCT joint bloodstream infections on APACHEⅡ score and SOFA score is important for assessing the severity and prognosis.
|
|
Received: 29 August 2016
|
|
|
|
|
|
|
Address: 1 North 2nd Street,
Zhongguancun, 