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| Clinical features of patients with Parkinson′s disease complicated with pneumonia admitted from emergency department |
| Zhang Li-ping,Ma Qing-bian |
| Department of Emergency, the Third Hospital of Peking University, Beijing 100191, China |
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Abstract Objective To analyze the clinical features of patients with Parkinson′s disease (PD) complicated with pneumonia admitted from emergency department. Methods We studied 190 patients with PD who enrolled in ER from September 2007 to September 2017.We analyzed the clinical characteristics, risk factors, etiological features and prognosis of patients with PD and pneumonia. Results ①Patients with PD complicated with pneumonia(n=75) were older, and had longer duration of PD and length of stay as well as higher mortality compared to patients without pneumonia(n=115, P<0.05).②Risk factors related to pneumonia were H&Y staging, dysphagia, and hypoproteinemia(P<0.001).③Gram-negative bacteria (82.6%) were the main etiological pathogens. Common pathogens were Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. ④16 cases (21.3%) died.Female, indwelling gastric tube, atrial fibrillation were high-risk factors for prognosis of PD with pneumonia. Conclusion Pneumonia in patients with PD may be closely related to the severity of PD, dysphagia and hypoalbuminemia. Gram-negative bacteria are the main pathogens. Patients with PD complicated with pneumonia have high mortality.
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Corresponding Authors:
Ma Qing-bian, E-mail: maqingbian@medmail.com.cn
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