急性肾损伤相关生物标志物研究现状

doi:10.3969/j.issn.1002-1949.2018.02.003

Chinese Journal of Critical Care Medicine

2018, Vol. 38

Issue (2): 108-110 DOI: 10.3969/j.issn.1002-1949.2018.02.003

Research advantages of the related biomarkers of acute kidney injury

Wang Yao,Wang Hong-liang

Intensive Care Unit, the Third Affiliated Hospital of Harbin Medical University, Harbin 150081, China

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Abstract Acute kidney injury (AKI) is a common severe disease in ICU. Diagnosis and grading standards of AKI are usually based on serum creatinine and urine output. There are some limitations. So it is necessary to find AKI related biomakers for early rapid diagnosis. The markers should have high specificity and sensitivity to indicate the occurrence, development and prognosis of disease situation. This article reviews the AKI related makers, such as NGAL, KIM-1, Cys C, to put forward a single marker for the diagnosis of AKI significance does not has obvious advantages.

Key words： Acute kidney injury(AKI)丨Makers丨Specificity

Received: 16 December 2017

Corresponding Authors: Wang Hong-liang, E-mail：icuwanghongliang@163.com

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Cite this article:

Wang Yao,Wang Hong-liang. Research advantages of the related biomarkers of acute kidney injury[J]. Chinese Journal of Critical Care Medicine, 2018, 38(2): 108-110.

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http://www.cnemergency.org.cn/EN/10.3969/j.issn.1002-1949.2018.02.003 OR http://www.cnemergency.org.cn/EN/Y2018/V38/I2/108

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