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| Influence on the haemodynamics index，APACHE Ⅱ，hospital stays for the patients with SIRS
combine with CLS by CRRT |
| LI Huan-gen，CHEN Wei-wen, ZHENG Wen-bo |
| Intensive Care Unit，Quanzhou First Hospital of Fujian Medical University，Quanzhou 362000，China |
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Abstract Objective To explore the influence on the haemodynamics index，APACHE Ⅱ，hospital stays for the
patients with systemic inflammatory response syndrome combine with capillary leak syndrome by
continuous renal replacement therapy（CRRT）. Methods Eighty- two cases of patients with systemic
inflammatory response syndrome combine with capillary leak syndrome were investigated;40 cases of
patients were treated by CRRT as the experiment group，and 42 cases of patients were not treated by CRRT as the control group. The patients in control group were treated by routine comprehensive
treatment; on the basis of the control group，the patients in experiment group were treated by CRRT.
The central venous pressure，mean arterial pressure，oxygenation index，heart rate，urine volume，in⁃
tra-abdominal pressure，extravascular lung water，pulmonary vascular permeability index，white blood
cell count，c-reactive protein，APACHEⅡ，hospital stays were compared. Results The MAP，OI，urine
volume in the experiment group were higher than those in the control group（92.16±11.01 vs. 84.15±
11.68）mm Hg，（231.06±33.68 vs. 189.48±31.97）mm Hg，（73.11±12.67 vs. 52.17±11.06）mL/h（P＜0.05）.
The levels of EVLW，PVPI in the experiment group were lower than those in the control group
（7.09±0.58 vs. 8.72±0.52）mL/kg,（2.27±0.82 vs. 3.85±0.80）%（P＜0.05）. The levels of WBC，CRP in
the experiment group were lower than those in the control group（10.59±3.15 vs. 14.81±3.56）×109/L,
（70.15±30.08 vs. 100.26±45.51）mg/L（P＜0.05）. The scores of APACHEⅡ，hospital stays for the
experiment group were lower than the control group（10.01±3.97 vs. 13.12±5.11），（85.97±20.08 vs.
135.16±25.17）h（P＜0.05）. Conclusion CRRT can improve the hemodynamic index，inflammatory
markers，microcirculation for the patients with systemic inflammatory response syndrome combine with
capillary leak syndrome; it can also promote urination，reduce the capillary permeability，and improve the prognosis.
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Received: 20 November 2015
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Corresponding Authors:
CHEN Wei-wen，E-mail: chenww2222@163.com
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