|
|
|
|
|
| The study on the value of using Chinese simlpe sequential organ failure assessment and quick sequential organ failure assessment for sepsis screening |
| Chen Xiao-yan, Li Yuan-hai, Wang Zheng-guang, Yao Jian-hua |
| Intensive Care Unit, Huangshan Shoukang Hospital, Huangshan 245000, China |
|
|
|
|
Abstract Objective To establish a new rapid screening score for sepsis based on the simplified SOFA (simple sequential organ failure assessment, sSOFA) score, which is the simplified SOFA score (Chinese sSOFA, C-sSOFA score) in Chinese, and provide reference for early detection of sepsis patients. Methods A retrospective analysis was performed in 209 patients admitted to the department of critical care medicine (ICU) from June 2014 to August 2018, including 107 patients in the sepsis group and 102 patients in the non-sepsis group. Each patient was subjected to C-sSOFA score and quick sequential organ failure assessment (qSOFA) score, and the receiver operating characteristic (ROC) curve was used to compare the value of the two scores in screening patients with sepsis. Results The sensitivity, specificity, positive prediction value, negative prediction value and Kappa value of C-sSOFA score and qSOFA score in screening patients with sepsis were 89.70% vs. 38.30%, 54.50%vs. 92.20%, 68.1% vs. 83.7%, 83.1% vs. 58.8% and 0.45 vs. 0.30, respectively. The area under the ROC curve of C-sSOFA score and qSOFA score were 0.721 (95%CI0.650-0.793, P<0.001) and 0.651 (95%CI0.576-0.726, P<0.001), respectively. Conclusion The new rapid screening score for sepsis, C-sSOFA score is better than qSOFA score in screening patients with sepsis.
|
|
|
|
Corresponding Authors:
Li Yuan-hai, E-mail： liyuanhai-1@163.com
|
|
|
|
| ［1］魏锋，洪志敏，董海涛，等. ICU重度脓毒症的流行病学特点及预后影响因素的分析［J］.中华医院感染学杂志， 2018， 28（10）：1469-1471,1484.
［2］苏和毅，莫泽珣，陈蕊，等. 胸腺肽α1干预治疗对脓毒症后的PICS老年患者免疫、代谢功能及预后的影响［J］. 实用医学杂志， 2018， 34（1）：119-123.
［3］谈昀,曾宪飞,白晓. 血清降钙素原对脓毒症严重程度评估及预后研究［J］. 现代检验医学杂志， 2014, 5:100-103.
［4］Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (sepsis-3)［J］. JAMA, 2016, 315(8):801-810.
［5］Dorsett M, Kroll M, Smith CS, et al. qSOFA has poor sensitivity for prehospital identification of severe sepsis and septic shock［J］. Prehosp Emerg Care, 2017, 21(4):489-497.
［6］Guirgis FW, Puskarich MA, Smotherman C, et al. Development of a simple sequential organ failure assessment score for risk assessment of emergency department patients with sepsis［J］. J Intensive Care Med， 2017, 1:885066617741284..
［7］王雪婷，高雪花，关银，等. 血降钙素原对脓毒症相关急性肾损伤的诊断价值［J］. 中国急救医学， 2018, 38（1）：80-83.
［8］张玲，张越新，黄春华，等. 脓毒症并发急性肾损伤患者临床特点及预后影响因素分析［J］. 中华医院感染学杂志， 2018， 28（14）：2105-2108.
［9］陈露,吴先龙. 血清乳酸联合降钙素原检测用于脓毒症致急性呼吸窘迫综合征预后判断的价值［J］. 浙江医学, 2018, 40(1):74-77.
［10］张德厚，陈义坤，刘大东.脓毒症患者早期血小板功能变化及预后分析［J］. 中华危重症医学杂志（电子版）， 2017， 10（1）：28-33. |
|
|
|
Address: 1 North 2nd Street,
Zhongguancun, 
