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| Mortality risk factors analysis of trauma patients with massive transfusion |
| Liu Yue-gao, Qian Yong-bing, Tian Rui, Jin Wei, Ge Fang-xia, Lv Hui, Lu Jian |
| Intensive Care Unit, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China |
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Abstract Objective: To explore the independent risk factors related to the mortality of massive transfusion trauma patients during the 30-day hospitalization. Methods: Retrospective cohort study (analysis) was performed for the trauma patients who received massive transfusion in Shanghai General Hospital from November 2006 to June 2015, potential risk factors resulted in the death of these trauma patients were analyzed via single and multiple factors logistic regression analysis. Results: Totally, 133 patients were included in the current study according to the inclusion criteria. Multivariable Logistic regression analysis screened the following independent risk factors that related to the mortality of massive transfusion patients during the 24 h hospitalization: hemoglobin (Hb, OR 6.664, P=0.021, 95%CI 1.332～33.326), fresh frozen plasma: concentration of red blood cells (FFP∶PRBC, OR 1.934, P=0.007, 95%CI 1.195～3.131); the independent risk factors that related to the mortality of massive transfusion patients during the 30-day hospitalization were as follow: sequential organ failure assessment (SOFA, OR 7.278, P=0.004, 95%CI 1.908～27.757), pelvic fractures (OR 3.080, P=0.039, 95%CI 1.060～8.951). Conclusion: Hb, FFP∶PRBC may be served as the independent risk factors that related to the mortality of massive transfusion patients during the 24 h hospitalization. SOFA, pelvic fractures may be served as the independent risk factors that related to the mortality of massive transfusion patients during the 30 d hospitalization.
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Received: 28 August 2017
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Corresponding Authors:
Lu Jian, E-mail: lujian@live.cn
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