ST2在急性心力衰竭中的预后价值

doi:10.3969/j.issn.1002-1949.2018.01.010

Chinese Journal of Critical Care Medicine

2018, Vol. 38

Issue (1): 41-45 DOI: 10.3969/j.issn.1002-1949.2018.01.010

ST2 and prognosis in acute heart failure

Meng Chong,Shang De-ya, Wang Juan

Provincial Hospital Affiliated to Shandong University, Jinan 250021, China

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Abstract ST2 could reduce myocardial fibrosis, inhibit myocardial hypertrophy, prevent myocardial apoptosis and improve heart function by the binding of IL-33. sST2 avidly binds IL-33 which results in interruption of the cardioprotective interaction. At present, firstly, ST2 in community population is certainly related to gender, but unclearly to age. Moreover, the diagnostic value of ST2 is negligible in patients with acute heart failure, but it can independently predict adverse cardiovascular events in those, especially the death and rehospitalization for worsen heart function. The last, serial measurement of the ST2 might play an important role in the prognosis and guidance of treatment.

Received: 28 August 2017

Corresponding Authors: Shang De-ya, E-mail: Sdsllysdy123@163.com

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Cite this article:

Meng Chong,Shang De-ya,Wang Juan. ST2 and prognosis in acute heart failure[J]. Chinese Journal of Critical Care Medicine, 2018, 38(1): 41-45.

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http://www.cnemergency.org.cn/EN/10.3969/j.issn.1002-1949.2018.01.010 OR http://www.cnemergency.org.cn/EN/Y2018/V38/I1/41

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