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| Relationship between adiponectin level and prognosis of acute respiratory distress syndrome in a cardiothoracic surgery ICU: a single center prospective cohort study |
| YE Lin，LV Fu—rong，JlANG Ying—ju |
| Department of Cardiothoracic Surgery．the First Affiliated Hospital，Chongqing Medical University，Chongqing 400016，China |
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Abstract Objective To analyze the prevalence of acute respiratory distress syndrome (ARDS)in a single cardiothoraeic surgery ICU and discuss the relationship between adiponectin(APN) level and ARDS clinical parameters，pathogenic condition and clinical outcome．Methods This is a prospective cohort study．Patients over 16 years old in cardiothoracic surgery ICU were studied．The time period was 12 months．ARDS type and clinical parameters were analyzed．The relationship between APN level and clinical parameters，severity of clinical manifestation and clinical outcomes were also studied． Results The morbidity of ARDS Waft,17．9％．The mortality was 25．8％．APACHE II score．PEEP were lower in the APN>5 mg／L group．while the APN<5 ms／L group were higher in pH．APN level in patients with less severe clinical manifestations was higher than that of severe group(P<0．05)． Conclusion ARDS is a common complication in the cardiothoracie surgery ICU．APN level is related to the severity of disease and clinical outcome．Lower level of APN may suggest a bad outcome and a high risk of ARDS death．
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Received: 27 October 2015
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Corresponding Authors:
JlANG Ying—ju,E—mail：jiangyingjiu@aliyun．com。
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