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| Effect of Liangge San on gastrointestinal dysfunction in patients with mechanical ventilation |
| LUO Ning, GAO Hong - mei, CAO Shu - hua, LI Yin, LI Hong - jie, FAN Wen, CHANG Wen - xiu. |
| Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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Abstract Objective Evaluate the effect of Liangge San on gastrointestinal dysfunction in patients with mechanical ventilation. Methods 80 patients admitted in ICU who treated with mechanical ventilation and combined with the injury of gastrointestinal function were chosen and rando mLy divided into control group and Liangge San treatment group, 40 patients in each group. All patients treated with mechanical ventilation, and gastrointestinal intervention treatment process according to AGI classification; on the basis of the control group, we gave Liangge San to the treatment group extra. We compared the IAP and AGI level between two groups before treatment and on the 1st, 3rd, 5th, 7th day after treatment. Results There were no statistical significant differences in IAP and AGI level between the two groups before treatment. On the 1st day after treatment, IAP increased significantly in both two groups(P < 0. 05), but not between the two groups both in IAP and AGI level. On the 3rd day after treatment, IAP decreased in both groups, and faster in treatment group, there was statistical significantdifferences between two groups ( P < 0. 05), but AGI level were still similar. On the 5th day after treatment, IAP were decreased further in both groups, and much faster in treatment group, AGI level was better in treatment group than control group too, there were statistical significant differences in IAP and AGI level between the two groups(P < 0. 05). On the 7th day after treatment, IAP were decreased further in both groups, and much faster in treatment group, IAP in treatment group were lower than normal; there were more statistical significant differences in IAP and AGI level between the two groups (P < 0. 05 ). Conclusion Liangge San can relieve the IAP and AGI level and improve the gastrointestinal symptoms in patients with mechanical ventilation.
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Received: 26 July 2015
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Corresponding Authors:
GAO Hongmei, E - mail:loloningning@ 163. com
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Address: 1 North 2nd Street,
Zhongguancun, 