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Abstract Objective To investigate risk factors and prognosis of systemic inflammatory re⁃ sponse syndrome（SIRS）caused by posterior circulation cerebral infarction（PCI）. Methods Clinical data of 108 acute PCI patients were analyzed retrospectively. According to diagnosis criteria of SIRS, all patients were divided into two groups: with SIRS group and without SIRS group within the 21 days after onset. The clinic records and laboratory data were analyzed by logistic regression to find potential risk factors of SIRS caused by PCI and contributors of prognosis. Results Forty- nine PCI patients had SIRS within the 21 days after onset. Four factors including history of diabetes, brainstem injury, NIHSS, dysphagia had statistics differences（P＜0.05）by univariate analysis. NIHSS（OR＝1.132, 95% CI 1.011~1.269, P＝0.032）, brainstem injury（OR＝4.044, 95%CI 1.129~14.494, P＝0.032）were the in⁃ dependent risk factors for SIRS caused by PCI proved by multivariate analysis. NIHSS（OR＝1.552, 95% CI 1.060~2.272, P＝0.024）influenced the prognosis of PCI patients with SIRS. Conclusion Risk fac⁃ tors associated with SIRS caused by PCI are degree of neurological deficits and injury of brainstem. Anddegree of neurological deficits affects the prognosis of PCI patients with SIRS.
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Received: 05 May 2016
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