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| Analysis of the epidemic reasons for the outbreak of the suspected outbreak of ICU resistant Acinetobacter Bauman in Tumor Hospital |
| Yang Li-xin, Jia Wei, Da chun-li, Fu Wen-ting, Li Shao-yu,Zhang Hui-wen |
| Department of Intensive Care Unit, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi 830011, China |
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Abstract Objective To analyze the epidemic factors of the outbreak of carbapenems-resis⁃ tant Acinetobacter Bauman（AB）, and to provide clinical evidence for the prevention and treatment ofAB infection in Tumor Hospital. Methods We analyzed the AB distribution patterns, the correlation be⁃ tween antibiotics use rate, intensity and drug resistance that in ICU of Xinjiang Tumor Hospital from Jan. 2013 to Dec. 2015 retrospectively. Single factor analysis and non-conditional logistic multivariate regres⁃ sion analysis were used to select the independent risk factors for AB infection. Results We collected 157 AB from 2013 to 2015, of which 76 showed MDR-AB, 18 showed XDR-AB, and the drug resistance increased year by year. The rates of AB detection in sputum, urine, blood, drainage and wound secretion were 80.3%, 9.5%, 2.5%, 2.5%, 2.5% respectively. The drug resistance increased with increased ratio and antibiotic use density, while quinolones showed stable trend. Single factor analysis showed the use of sugar cortical hormone and hydrocarbon vinyl antibiotic, mechanical ventilation, in ICU time＞7 days and the broad-spectrum antibiotics using time＞7 days were risk factors for AB infection. Non-condi⁃ tional logistic multivariate regression analysis showed mechanical ventilation, in ICU time＞7 days, the use of hydrocarbon vinyl antibiotic, and the broad-spectrum antibiotics using time＞7 days were inde⁃ pendent risk factors for AB infection. Conclusion AB infection is mainly in the lower respiratory tract in ICU of the Tumor Hospital. The prevalence of drug resistance is positively correlated with the use of broad spectrum antibiotics. Mechanical ventilation, ICU time＞7 days, the use of hydrocarbon vinyl anti⁃ biotic, and the broadspectrum antibiotics using time＞7 days were independent risk factors for AB infec⁃ tion. So, carrying clusters of prevention and control measures of AB can prevent the incidence of AB
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Received: 18 March 2016
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Corresponding Authors:
Zhang hui-wen, E-mail: 35834271@qq.com
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