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The relationship of glucose variability and prognosis in patients with acute myocardial infarction during percutaneous coronary intervention |
Liu Mei, Fan Xue-peng, Zhang Wei-ming, Shang Xiaoke |
ICU,Wuhan No. 1 Hospital, Wuhan 430022, China |
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Abstract Objective To explore the relationship between a prognosis and the glucose variability in patients with acute myocardial infarction(AMI)during percutaneous coronary intervention(PCI). Methods The study included 216 AMI patients who had undergone PCI. The patients were divided into tertiles according the glucose variability. The coronary lesions, TIMI flow post-PCI, echocardiography after one week, and the rate of major adverse cardiovascular events(MACEs)within 30 days were compared among the three groups. Results By the increasing of the glucose variability, the coronary lesions and TIMI flow post-PCI showed worse results. The rate of MACEs was highest in the Q3 group which had the highest glucose variability. Echocardiography showed LVDd increased and LVEF decreased with the increase of the glucose variability. The number of patients with caridiac function Killp Ⅲ or IV was the biggest in Q3 group on the 30th day. Conclusion Glucose variability can be used to evaluate the coronary lesions and prognosis of patients with AMI underwent PCI.
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Received: 14 October 2015
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