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| Serum total testosterone in male critically ill patients: correlations with APACHE Ⅱ score |
| Hui Zhi-yan, Fang Ge, Zhang Xu, Yuan Qing-xia |
| Department of Critical Care Medicine, Yan′an University Affiliated Hospital, Yan′an 716000, China |
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Abstract Objective To investigate serum total testosterone(TT) in male critically ill patients of intensive care unit (ICU) and the correlations with acute physiology and the evaluation of chronic health status assessment system (APACHE Ⅱ). Methods The 75 male patients admitted to ICU of Yan′an University Affiliated Hospital from May 2016 to March 2018 were enrolled. All patients were calculated APACHE Ⅱ score within the first 24 h after ICU and monitored for serum TT in second morning. They were divided into two groups according to the score: group A<20 score (n=25)and group B≥20 score(n=50), and compared the levels of serum TT; According to age ［group C<50 years old （n=28）, group D≥50 years old （n=47）］ were divided into two groups, and compared serum TT levels; furthermore, analyzed the correlations between serum TT and APACHEⅡ score with Pearson correlation analysis. Results According to the APACHE Ⅱ score, the serum TT［(5.39±1.83)ng/dL］ in group A was significantly higher than that in group B［(2.68±2.04)ng/dL,P＜0.01］. There was no significant difference in serum TT between two groups were divided according to age. There was a significant negative correlation between serum TT and APACHE Ⅱ score(r=-0.70, P=0.00). Conclusion The lower serum TT, the more serious the disease, and there is a good correlation between the serum TT and APACHE Ⅱ score in the critically ill male patients. This implied that it was also important to monitor serum TT earlier in order to assess the severity of the diseases except the APACHE Ⅱ score in critical ill male patients.
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| About author:: Hui Zhi-yan, E-mail: hzy1149@163.com |
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