PICU治疗的自发性脑出血患儿临床特征与预后因素研究

doi:10.3969/j.issn.1002-1949.2018.06.011

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摘要目的评价在儿童重症监护病房（PICU）治疗的自发性脑出血（sICH）患儿的临床特征与预后影响因素。方法收集在德阳市第二人民医院PICU治疗的123例14岁以下sICH患儿的临床资料，分析患儿的临床特征、治疗方法，采用单变量与COX多变量比例模型，评价影响患儿死亡与存活患儿预后的相关因素。结果患儿的入院格拉斯哥昏迷（GCS）评分为（7.45±3.10）分。sICH患儿最重要病因为血管畸形（35.8%，44/123），患儿总病死率为24.4%（30/123）。COX多变量比例模型分析表明，中线移位与患儿病死率呈正相关（HR=5.731，95%CI1.869～17.574，P=0.003），入院GCS评分较低与存活患儿预后不良显著相关（HR=3.248，95%CI 1.556～6.778，P=0.003）。结论 sICH是严重影响患儿生命安全和身体健康的重症疾病，主要致病因素为血管畸形突然破裂。中线移位和入院GCS评分是影响患儿病死率和神经预后的重要因素。

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	冯爱平
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关键词 ：儿童, 自发性脑出血(sICH), 预后, 临床特征

作者简介: 冯爱平（1967-），男，主任医师，科主任，E-mail:jackfengap@sina.com

引用本文:

冯爱平，王文，杜陈，乔伟，黄其军. PICU治疗的自发性脑出血患儿临床特征与预后因素研究[J]. 中国急救医学, 2018, 38(6): 510-.
Feng Ai-ping, Wang Wen, Du Chen, Qiao Wei, Huang Qi-jun. Clinical and prognostic factors of spontaneous intracerebral hemorrhage in children treated with PICU. Chinese Journal of Critical Care Medicine, 2018, 38(6): 510-.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2018.06.011 或 http://www.cnemergency.org.cn/CN/Y2018/V38/I6/510

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