多糖包被及其在失血性休克发展进程中的作用

doi:10.3969/j.issn.1002-1949.2018.03.022

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摘要多糖包被是血管内皮双层屏障的重要组成部分，具有抗炎、抗凝等生理功能；失血性休克引起多糖包被的结构破坏，进而在血管高通透性、过度炎症反应、血液高凝的发生过程中发挥重要作用，成为失血性休克发生机制之一。本文综述多糖包被的结构、功能及其在失血性休克发展进程中的作用，为以多糖包被为切入点，防治失血性休克提供新思路。

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	赵梦
	赵自刚

关键词 ：多糖包被, 失血性休克, 毛细血管渗漏综合征（CLS）

收稿日期: 2017-12-09

基金资助:国家自然科学基金面上项目（81670446）

通讯作者: 赵自刚(1974-)，男，博士，教授，硕士生导师，E-mail:zzghyl@126.com。

作者简介: 赵梦（1991-），女，硕士研究生, E-mail:864748193@qq.com。

引用本文:

赵梦，赵自刚. 多糖包被及其在失血性休克发展进程中的作用 [J]. 中国急救医学, 2018, 38(3): 273-278.
Zhao Meng, Zhao Zi-Gang. Glycocalyx and its role during hemorrhagic shock . Chinese Journal of Critical Care Medicine, 2018, 38(3): 273-278.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2018.03.022 或 http://www.cnemergency.org.cn/CN/Y2018/V38/I3/273

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