王光英，赵浩天，龙玲，王华伟，蒋小芝，贺法强，张之阳，赵鹤龄. 碳酸氢钠在感染性休克患者中的应用现况和作用
[J]. 中国急救医学, 2018, 38(3): 256-259.
Wang Guang-ying, Zhao Hao-tian, Long Ling, Wang Hua-wei, Jiang Xiao-zhi, He Fa-qiang, Zhang Zhi-yang, Zhao He-ling. Epidemiology and application of sodium bicarbonate in patients with septic shock
. Chinese Journal of Critical Care Medicine, 2018, 38(3): 256-259.
［1］Ricci Z, Ronco C. Pathogenesis of acute kidney injury during sepsis ［J］. Curr Drug Targets, 2009, 10(12):1179-1183.
［2］朱大年，王庭槐.生理学［M］.第8版.北京：人民卫生出版社, 2015：218-224.
［3］Kraut JA, Madias NE. Lactic Acidosis: Current Treatments and Future Directions［J］. Am J Kidney Dis, 2016, 68(3):473-482.
［4］Kimmoun A, Novy E, Auchet T, et al. Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside ［J］. Crit Care, 2015, 19:175.
［5］Jung B, Rimmele T, Le Goff C, et al. Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study［J］. Crit Care, 2011, 15(5):R238.
［6］Cariou A, Vinsonneau C, Dhainaut JF. Adjunctive therapies in sepsis: an evidence-based review［J］. Crit Care Med, 2004, 32(11 Suppl):S562-570.
［7］Noritomi DT, Soriano FG, Kellum JA, et al. Metabolic acidosis in patients with severe sepsis and septic shock: a longitudinal quantitative study［J］. Crit Care Med, 2009, 37(10):2733-2739.
［8］Adeva-Andany MM, Fernández-Fernández C, Mourio-Bayolo D, et al. Sodium bicarbonate therapy in patients with metabolicacidosis［J］. Scientific World Journal， 2014, 2014:627 673.
［9］Kim HJ, Son YK, An WS. Effect of sodium bicarbonate administration on mortality in patients with lactic acidosis: a retrospective analysis［J］. PLoS One, 2013, 8(6):e65 283.
［10］Lee SM, Kim SE, Kim EB, et al. Lactate clearance and vasopressor seem to be predictors for mortality in severe sepsis patients with lactic acidosis supplementing sodium bicarbonate: aretrospective analysis［J］. PloS One, 2015, 10(12):e0 145 181.
［11］Montagnani A, Nardi R. Lactic acidosis, hyperlactatemia and sepsis［J］. Italian J Med, 2016， 10(4):282-288.
［12］Taghizadieh A, Pouraghaei M, Moharamzadeh P, et al. Comparison of end-tidal carbon dioxide and arterial blood bicarbonate levels in patients with metabolic acidosis referred to emergency medicine［J］. J Cardiovasc Thorac Res, 2016, 8(3):98-101.
［13］El-Solh AA, Abou JP, Porhomayon J. Bicarbonate therapy in the treatment of septic shock: a second look［J］. Intern Emerg Med, 2010, 5(4):341-347.
［14］Dellinger RP, Levy MM, RhodesA, et al. Surviving sepsis campaign: international guidelines for management of severe sepsisand septic shock, 2012［J］. Crit Care Med, 2013, 41(2):580-637.
［15］Rhodes A,Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016［J］. Intensive Care Med, 2017, 43(3):304-377.
［16］Boyd JH, Walley KR. Is there a role for sodium bicarbonate in treating lactic acidosis from shock ［J］. Curr Opin Crit Care, 2008, 14(4):379-383.
［17］Duman A, Akoz A, Kapci M, et al. Prognostic value of neglected〖JP〗 biomarker in sepsis patients with the old and new criteria: predictive role of lactate dehydrogenase［J］. Am J Emerg Med, 2016, 34(11):2167-2171.
［18］陈小枫, 叶纪录, 朱志云. 碳酸氢钠在感染性休克致低灌注性乳酸酸中毒时的分阶段应用［J］. 中华危重病急救医学, 2013, 25(1):24-27.
［19］Fang ZX, Li YF, Zhou XQ. Effects of resuscitation with crystalloid fluids on cardiac function in patients with severe sepsis［J］. BMC Infect Dis, 2008, 8:50.
［20］Marhong J, Fan E. Carbon dioxide in the critically ill: too much or too little of a good thing ［J］. Respir Care, 2014, 59(10):1597-1605.
［21］Cooper DJ, Walley KR, Wiggs BR, et al. Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acid osis. A prospective, controlled clinical study［J］. Ann Intern Med, 1990, 112(7):492-498.
［22］Velissaris D, Karamouzos V, Ktenopoulos N, et al. The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate［J］. Crit Care Res Pract, 2015, 2015:605 830.
