创伤患者大量输血策略及研究进展

doi:10.3969/j.issn.1002-1949.2019.06.018

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摘要出血是创伤性死亡的主要原因。严重创伤发生大量失血，患者常常在起初几个小时内因失血性休克导致死亡。因此，治疗的主旨包括尽早识别失血性休克的风险，实施止血复苏，并同时启动大量输血方案(massive transfusion protocol, MTP)，以预防或纠正创伤性凝血病（trauma-induced coagulopathy，TIC）及病程进展引发的更为严重的生理紊乱，甚至死亡。早期使用氨甲环酸（TXA）治疗，可能有助于预防纤维蛋白溶解。黏弹性检测在评估进一步纤维蛋白溶解方面优于传统凝血检测，为治疗提供一定指导。本文结合近年来国内外有关创伤大量输血的策略及研究进展做一综述，为临床实践提供依据。

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	宋广平
	李代红

关键词 ：大量输血方案（MTP）, 严重创伤, 输血策略

通讯作者: 李代红（1966-），女，主任技师，输血科主任，E-mail: ldh_hla@163.com。

作者简介: 宋广平（1982-），女，主管技师，E-mail：songgp728@163.com。

引用本文:

宋广平，李代红. 创伤患者大量输血策略及研究进展[J]. 中国急救医学, 2019, 39(6): 605-609.
Song Guang-ping, Li Dai-hong. The strategy and research progress of massive blood transfusion in traumatic patients. Chinese Journal of Critical Care Medicine, 2019, 39(6): 605-609.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2019.06.018 或 http://www.cnemergency.org.cn/CN/Y2019/V39/I6/605

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