急诊科心肺复苏结局与肾上腺素用量关系的研究

doi:10.3969/j.issn.1002-1949.2019.06.003

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摘要目的研究急诊科心肺复苏（CPR）的结局和抢救中累计使用的肾上腺素剂量之间的相关性。方法回顾性分析2008年1月至2018年6月期间北京协和医院急诊科进行CPR的所有患者资料，统计患者的性别、年龄、心脏骤停（CA）病因、肾上腺素累计剂量和CPR结局，CPR结局包括有无自主循环恢复、是否存活出院，以及是否为良好神经系统功能存活出院，其中以是否为良好神经系统功能存活出院为主要分析目标。统计分析肾上腺素累计剂量和CPR结局之间的相关性。结果共有4843例CA患者，纳入1391例患者为研究对象，530例（38.1%）恢复自主循环，49例（3.5%）存活出院，35例（2.5%）具有良好神经系统功能存活出院。肾上腺素累计剂量＞5 mg者与CPR结局差的相关性有统计学意义（P<0.05）。结论肾上腺素累计超过5 mg的CPR患者结局明显偏差，具有良好神经功能存活出院率为0。

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	徐胜勇
	朱华栋
	于学忠

关键词 ：心脏骤停(CA), 心肺复苏(CPR), 肾上腺素

基金资助:国家临床重点专科建设项目（卫办医政函［2012］650号）

通讯作者: 朱华栋（1970-），男，主任医师，博士生导师，急诊科主任，E-mail：huadongzhu@hotmail.com。

作者简介: 徐胜勇（1982-），男，硕士，主治医师，主任助理，E-mail：xushengyong99@163.com。

引用本文:

徐胜勇，朱华栋，于学忠. 急诊科心肺复苏结局与肾上腺素用量关系的研究[J]. 中国急救医学, 2019, 39(6): 538-541.
Xu Sheng-yong, Zhu Hua-dong, Yu Xue-zhong. The relationship between the outcome of cardiopulmonary resuscitation and the dosage of epinephrine in emergency department. Chinese Journal of Critical Care Medicine, 2019, 39(6): 538-541.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2019.06.003 或 http://www.cnemergency.org.cn/CN/Y2019/V39/I6/538

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