摘要目的 探讨血清白蛋白(Alb)及中性粒细胞/淋巴细胞比值(NLR)预测创伤性脑出血(TICH)患者预后的价值。 方法 选取海南省第三人民医院收治的TICH患者240例,根据28 d预后情况分为存活组(n=187)和死亡组(n=53),检测入院第1、3、5天血清Alb及NLR水平变化。应用受试者工作特征(ROC)曲线,分析各时间点血清Alb及NLR预测TICH患者预后的价值。 结果 死亡组第1、3、5天血清Alb(g/L)水平均明显低于存活组(32.75±5.62 vs.39.35±6.28,29.30±4.58 vs. 43.46±7.52,22.37±4.20 vs. 45.42±7.64,均P<0.05),而死亡组第1、3、5天NLR均明显高于存活组(6.03±2.35 vs. 4.36±1.34,7.14±2.38 vs. 3.36±1.25,8.50±3.25 vs. 2.14±0.92,均P<0.05)。ROC曲线显示,第3天血清Alb及NLR水平预测TICH患者预后的最佳界值分别为31.40、5.24,第3天两项联合预测TICH患者预后的AUC(95%CI)为0.924(0.860~0.973),明显高于单项Alb[0.834(0.781~0.892)]及NLR的AUC[0.850(0.780~0.897)],其敏感度和特异度分别为92.6%和87.3%。 结论 血清Alb及NLR水平变化与TICH患者的病情相关,第3天两项联合检测对TICH患者预后的预测价值较高。
卓芬,肖华,黄娟娟,蔡月红. 血清白蛋白及中性粒细胞/淋巴细胞比值预测创伤性脑出血患者预后的价值[J]. 中国急救医学, 2019, 39(5): 408-411.
Zhuo Fen, Xiao Hua, Huang Juan-juan, Cai Yue-hong. Prognostic value of serum albumin and neutrophil/lymphocyte ratio in patients with traumatic cerebral hemorrhage. Chinese Journal of Critical Care Medicine, 2019, 39(5): 408-411.
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