创伤大输血患者死亡危险因素分析

doi:10.3969/j.issn.1002-1949.2018.01.013

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摘要目的：探讨创伤大输血患者院内死亡的独立危险因素。方法：回顾性队列研究分析2006-11~2015-06上海交通大学附属第一人民医院危重病科接受过大输血方案治疗的所有创伤大出血患者。通过单因素和多因素Logistic回归分析法对23个潜在影响创伤大输血患者死亡相关危险因素进行研究。结果： 133例患者符合纳入研究。多因素Logistic回归分析筛选出与创伤大输血患者住院24 h死亡相关独立危险因素有初始血红蛋白（Hb，OR 6.664， P=0.021, 95%CI 1.332~33.326）、新鲜冰冻血浆∶浓缩红细胞比例［（FFP∶PRBC），OR 1.934，P=0.007, 95%CI 1.195~3.131）］；住院30 d死亡相关的独立危险因素有序贯器官衰竭估计评分（SOFA评分，OR 7.278， P=0.004，95%CI 1.908～27.757）、骨盆骨折（OR 3.080，P=0.039， 95%CI 1.060~8.951）。〖HTH〗结论〓〖HTSS〗初始Hb、FFP∶〖KG-*2〗PRBC可能是创伤大输血患者院内24 h死亡相关的独立危险因素；SOFA评分、骨盆骨折可能是创伤大输血患者院内30 d死亡相关的独立危险因素。

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	刘月高
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	吕慧
	陆健

收稿日期: 2017-08-28

基金资助:上海卫生计生系统重要薄弱学科建设计划（2016ZB0205）

通讯作者: 陆健（1980-），男，博士，主治医师，E-mail:lujian@live.cn。

作者简介: 刘月高（1988-），男，硕士，住院医师。E-mail：1807835761@qq.com。

引用本文:

刘月高，钱永兵，田锐，金卫，葛芳侠，吕慧，陆健. 创伤大输血患者死亡危险因素分析[J]. 中国急救医学, 2018, 38(1): 57-62.
Liu Yue-gao, Qian Yong-bing, Tian Rui, Jin Wei, Ge Fang-xia, Lv Hui, Lu Jian. Mortality risk factors analysis of trauma patients with massive transfusion. Chinese Journal of Critical Care Medicine, 2018, 38(1): 57-62.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2018.01.013 或 http://www.cnemergency.org.cn/CN/Y2018/V38/I1/57

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