氧化应激在脓毒症器官功能损伤中的作用

doi:10.3969/j.issn.1002-1949.2019.04.019

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摘要脓毒症是因宿主对感染的反应失调而导致的危及生命的器官功能障碍，是临床急危重症患者的严重并发症，可进展为重症脓毒症、感染性休克，最终导致死亡。氧化应激作为脓毒症进展为重度脓毒症、感染性休克的重要原因，近年受到重视。本文对脓毒症时氧化应激在人体器官功能损伤中的作用机制作一综述。

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	王兴程
	杨磊
	温霄雄
	王斌生
	彭超
	柴琛

关键词 ：脓毒症, 氧化应激, 发病机制

基金资助:兰州市科技发展计划项目（2015-2-65）

通讯作者: 柴琛（1974-），男，博士，硕士生导师，教授，科主任，E-mail:chasechai@126.com。

作者简介: 王兴程（1993-），男，硕士研究生，E-mail:1499048708@qq.com。

引用本文:

王兴程，杨磊，温霄雄，王斌生，彭超，柴琛. 氧化应激在脓毒症器官功能损伤中的作用[J]. 中国急救医学, 2019, 39(4): 388-392.
Wang Xing-cheng, Yang Lei, Wen Xiao-xiong, Wang Bin-sheng, Peng Chao, Chai Chen. Role of oxidative stress in organ dysfunction of sepsis. Chinese Journal of Critical Care Medicine, 2019, 39(4): 388-392.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2019.04.019 或 http://www.cnemergency.org.cn/CN/Y2019/V39/I4/388

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