GRACE评分对急诊胸痛患者30d和6个月主要不良心血管事件的预测价值

doi:10.3969/j.issn.1002-1949.2017.12.012

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摘要目的：探讨GRACE评分对急诊室胸痛患者30 d和6个月主要不良心血管事件(MACE)的预测价值。方法：前瞻性队列临床观察研究方法对2012-03-17～2013-08-14在我院急诊因急性胸痛首诊的、年龄≥18岁患者进行观察。记录患者临床资料、GRACE评分、30 d和6个月MACE情况。结果：纳入研究的493例急性胸痛患者，30 d和6个月随访中，分别有32例（6%）和38例（7%）发生MACE。Logistic回归分析数据可见，GRACE评分、性别、吸烟史对急性胸痛患者30 d和6个月的MACE发生有预测意义。GRACE评分预测胸痛患者30 d MACE发生的曲线下面积(area under curve，AUC) 为0.815（95% CI 0.778～0.849），Cutoff值为174分，而预测胸痛患者6个月死亡的AUC为0.807（95% CI 0.769～0.841），Cutoff值为173分。结论： GRACE评分可以有效预测急诊急性胸痛患者30 d和6个月是否发生MACE。

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	李敏
	江慧琳
	李云妹
	莫均荣
	茅海峰
	田朝伟
	林珮仪
	陈晓辉

收稿日期: 2017-09-15

基金资助:广州市属高校科研立项（1201610645）；广州市医学重点学科建设项目（2017-2019年）

通讯作者: 陈晓辉（1965-），男，主任医师，博士生导师， E-mail：cxhgz168@126.com

作者简介: 李敏（1975-），女，硕士，主治医师， E-mail：limin1606@126.com

引用本文:

李敏,江慧琳,李云妹,莫均荣,茅海峰,田朝伟,林珮仪,陈晓辉. GRACE评分对急诊胸痛患者30d和6个月主要不良心血管事件的预测价值[J]. 中国急救医学, 2017, 37(12): 1123-1128.
Li Min, Jiang Hui-lin, Li Yun-mei, Mo Jun-rong, Mao Hai-feng, Tian Chao-wei, Lin Pei-yi, Chen Xiao-hui. The predictive value of GRACE score for 30-day and 6-month major adverse cardiovascular events in Emergency Departments patients with acute chest pain. Chinese Journal of Critical Care Medicine, 2017, 37(12): 1123-1128.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2017.12.012 或 http://www.cnemergency.org.cn/CN/Y2017/V37/I12/1123

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