脓毒性休克伴心肌抑制患者死亡风险分析

doi:10.3969/j.issn.1002-1949.2018.09.009

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摘要目的分析脓毒性休克伴心肌抑制患者的死亡风险。方法入选2015~2016年入住ICU的脓毒性休克患者，射血分数（EF）＜50%纳入心肌抑制组，EF≥50%纳入非心肌抑制组。比较两组患者入院6 h内 CRP、PCT、Lac，入院24~48 h CRP、PCT、Lac、BNP、cTnI、SOFA评分、去甲肾上腺素平均剂量。多因素Cox风险回归法分析脓毒症患者死亡风险，并比较两组的死亡风险。结果 132例患者纳入研究，心肌抑制组24~48 h Lac、BNP、cTnI、SOFA评分、去甲肾上腺素平均剂量较非心肌抑制组高，差异有统计学意义(P＜0.05)。多因素Cox风险回归分析显示，入院24~48 h Lac、BNP、cTnI、SOFA评分、去甲肾上腺素平均剂量及心肌抑制是脓毒性休克患者死亡的危险因素，差异有统计学意义（P＜0.05）。其中心肌抑制组患者14 d死亡风险较非心肌抑制组增高95.2%，差异有统计学意义(P＜0.05)。分析14 d后存活患者1年内生存情况，两组差异无统计学意义。结论心肌抑制患者14 d死亡风险增加95.2%。14 d后存活患者1年内死亡风险无差异。

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	吴丁烨
	高嵩
	衡军锋
	严洁

关键词 ：脓毒性休克, 心肌抑制, 死亡风险

通讯作者: 严洁（1961-），女，主任医师，硕士生导师，科主任，E-mail：yjeast@163.com。

作者简介: 吴丁烨（1982-），男，硕士，主治医师，E-mail：121551064@qq.com。

引用本文:

吴丁烨，高嵩，衡军锋，严洁. 脓毒性休克伴心肌抑制患者死亡风险分析[J]. 中国急救医学, 2018, 38(9): 786-789.
Wu Ding-ye, Gao Song, Heng Jun-feng, Yan Jie. Analysis of the mortality risk in septic shock patients with myocardial depression. Chinese Journal of Critical Care Medicine, 2018, 38(9): 786-789.

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http://www.cnemergency.org.cn/CN/10.3969/j.issn.1002-1949.2018.09.009 或 http://www.cnemergency.org.cn/CN/Y2018/V38/I9/786

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